Polycations sensitize enteric bacteria to antibiotics.

  title={Polycations sensitize enteric bacteria to antibiotics.},
  author={Martti Vaara and Timo Vaara},
  journal={Antimicrobial agents and chemotherapy},
  volume={24 1},
Polymyxin B nonapeptide, a polymyxin B derivative which lacks the fatty acyl part and the bactericidal activity of polymyxin, was shown to sensitize smooth encapsulated Escherichia coli (O18:K1) and smooth Salmonella typhimurium to hydrophobic antibiotics (novobiocin, fusidic acid, erythromycin, clindamycin, nafcillin, and cloxacillin). The polymyxin B nonapeptide-treated bacteria were as sensitive to these antibiotics as are deep rough mutants. A lysine polymer with 20 lysine residues (lysine… CONTINUE READING


Publications citing this paper.
Showing 1-10 of 47 extracted citations


Publications referenced by this paper.

Similar Papers

Loading similar papers…