Polyarteritis nodosa related to hepatitis B virus. A prospective study with long-term observation of 41 patients.

@article{Guillevin1995PolyarteritisNR,
  title={Polyarteritis nodosa related to hepatitis B virus. A prospective study with long-term observation of 41 patients.},
  author={L{\"o}ic Guillevin and François Lhote and Pascal Cohen and F Sauvaget and Bernard Jarrousse and Olivier Lortholary and Laure H{\'e}l{\`e}ne No{\"e}l and Christian Tr{\'e}po},
  journal={Medicine},
  year={1995},
  volume={74 5},
  pages={238-53}
}
Hepatitis B virus (HBV)-related polyarteritis nodosa (PAN) is a rare disease whose frequency has been decreasing over the past 10 years. We evaluated 41 patients with HBV-related PAN to determine the circumstances leading to infection, the clinical features of vasculitis, the prognostic factors, and the response to therapy. Most patients were first treated briefly with corticosteroids, and all were included in 2 nonrandomized prospective therapeutic trials of an antiviral agent (35 patients… CONTINUE READING
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