Polyanionic hydrogel as a gastric retentive system.

  title={Polyanionic hydrogel as a gastric retentive system.},
  author={Sam H Leung and Brian K. Irons and Joseph R. Robinson},
  journal={Journal of biomaterials science. Polymer edition},
  volume={4 5},
Gastric emptying of a polyanionic hydrogel, polycarbophil (PC), from the canine stomach was studied using a duodenal cannulation technique. The basis of the study is to employ a certain quantity of swelling hydrogel that, by virtue of its swollen size and viscosity, converts a fasted stomach to a fed state and resists discharge from the stomach for an… CONTINUE READING