Polyamines metabolism and breast cancer: state of the art and perspectives

@article{Cervelli2014PolyaminesMA,
  title={Polyamines metabolism and breast cancer: state of the art and perspectives},
  author={Manuela Cervelli and Stefano Pietropaoli and Fabrizio Signore and Roberto Amendola and Paolo Mariottini},
  journal={Breast Cancer Research and Treatment},
  year={2014},
  volume={148},
  pages={233-248}
}
Abstract Breast cancer (BC) is a common disease that generally occurs in women over the age of 50, and the risk is especially high for women over 60 years of age. One of the major BC therapeutic problems is that tumors initially responsive to chemotherapeutic approaches can progress to more aggressive forms poorly responsive to therapies. Polyamines (PAs) are small polycationic alkylamines, naturally occurring and essential for normal cell growth and development in eukaryotes. The intracellular… CONTINUE READING
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