Polyamines in drug discovery: from the universal template approach to the multitarget-directed ligand design strategy.

Abstract

The search for drugs to save, preserve, and enhance our lives has long posed great challenges to human effort. Since early times, thanks to the pioneering work of alchemists and then medicinal chemists, humanity has benefited enormously fromdrug discovery.Nowadays, sophisticated procedures for drug synthesis and target elucidation allow us to design… (More)
DOI: 10.1021/jm100293f

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