Polyamine synthesis from proline in the developing porcine placenta.

  title={Polyamine synthesis from proline in the developing porcine placenta.},
  author={Guoyao Wu and Fuller W Bazer and Jianbo Hu and Gregory A. Johnson and Thomas E Spencer},
  journal={Biology of reproduction},
  volume={72 4},
Polyamines (putrescine, spermidine, and spermine) are essential for placental growth and angiogenesis. However, little is known about polyamine synthesis in the porcine placenta during conceptus development. The present study was conducted to test the hypothesis that arginine and proline are the major sources of ornithine for placental polyamine production in pigs. Placentae, amniotic fluid, and allantoic fluid were obtained from gilts on Days 20, 30, 35, 40, 45, 50, 60, 90, and 110 of the 114… CONTINUE READING


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Recent advances in arginine metabolism

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