Polyamine synthesis and interconversion by the Microsporidian Encephalitozoon cuniculi.

@article{Bacchi2001PolyamineSA,
  title={Polyamine synthesis and interconversion by the Microsporidian Encephalitozoon cuniculi.},
  author={Cyrus J. Bacchi and Schennella Lane and Louis M Weiss and Nigel Yarlett and Peter M. Takvorian and Ann Cali and Murray Wittner},
  journal={The Journal of eukaryotic microbiology},
  year={2001},
  volume={48 3},
  pages={374-81}
}
Polyamines are small cationic molecules necessary for growth and differentiation in all cells. Although mammalian cells have been studied extensively, particularly as targets of polyamine antagonists, i.e. antitumor agents, polyamine metabolism has also been studied as a potential drug target in microorganisms. Since little is known concerning polyamine metabolism in the microsporidia, we investigated it in Encephalitozoon cuniculi, a microspordian associated with disseminated infections in… CONTINUE READING

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