Polyamine inhibition of transbilayer movement of plasma membrane phospholipids in the erythrocyte ghost.

@article{Bratton1994PolyamineIO,
  title={Polyamine inhibition of transbilayer movement of plasma membrane phospholipids in the erythrocyte ghost.},
  author={Donna L. Bratton},
  journal={The Journal of biological chemistry},
  year={1994},
  volume={269 36},
  pages={22517-23}
}
The resting plasma membrane of circulating blood cells demonstrates an asymmetric distribution of the phospholipid classes across the bilayer that is altered during cellular activation. To better understand the mechanisms governing transbilayer distribution of phospholipids, studies were conducted using the erythrocyte ghost, in which plasma membrane leaflet distribution of phospholipids can be readily probed. Preparation of ghosts by hypotonic lysis at increasingly high dilution markedly… CONTINUE READING