Polyamine depletion alters the relationship of F-actin, G-actin, and thymosin beta4 in migrating IEC-6 cells.

Abstract

The cause of reduced migration ability in polyamine-deficient cells is not known, but their actin cytoskeleton is clearly abnormal. We depleted polyamines with alpha-difluoromethylornithine (DFMO) in migrating cells with or without stimulation by epidermal growth factor (EGF) and investigated filamentous (F-) actin, monomeric (G-) actin, and thymosin beta4… (More)

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@article{McCormack1999PolyamineDA, title={Polyamine depletion alters the relationship of F-actin, G-actin, and thymosin beta4 in migrating IEC-6 cells.}, author={Shelley A. McCormack and R. M. Ray and Patrick M. Blanner and L. R. Johnson}, journal={The American journal of physiology}, year={1999}, volume={276 2 Pt 1}, pages={C459-68} }