Polyadenylation regulates the stability of Trypanosoma brucei mitochondrial RNAs.

@article{Ryan2003PolyadenylationRT,
  title={Polyadenylation regulates the stability of Trypanosoma brucei mitochondrial RNAs.},
  author={Christopher M Ryan and Kevin T. Militello and Laurie K. Read},
  journal={The Journal of biological chemistry},
  year={2003},
  volume={278 35},
  pages={32753-62}
}
Polyadenylation of RNAs plays a critical role in modulating rates of RNA turnover and ultimately in controlling gene expression in all systems examined to date. In mitochondria, the precise mechanisms by which RNAs are degraded, including the role of polyadenylation, are not well understood. Our previous in organello pulse-chase experiments suggest that poly(A) tails stimulate degradation of mRNAs in the mitochondria of the protozoan parasite Trypanosoma brucei (Militello, K. T., and Read, L. K… CONTINUE READING