PolyDoms: a whole genome database for the identification of non-synonymous coding SNPs with the potential to impact disease

@inproceedings{Jegga2007PolyDomsAW,
  title={PolyDoms: a whole genome database for the identification of non-synonymous coding SNPs with the potential to impact disease},
  author={Anil G. Jegga and Sivakumar Gowrisankar and Jing Chen and Bruce J. Aronow},
  booktitle={Nucleic Acids Research},
  year={2007}
}
As knowledge of human genetic polymorphisms grows, so does the opportunity and challenge of identifying those polymorphisms that may impact the health or disease risk of an individual person. A critical need is to organize large-scale polymorphism analyses and to prioritize candidate non-synonymous coding SNPs (nsSNPs) that should be tested in experimental and epidemiological studies to establish their context-specific impacts on protein function. In addition, with emerging high-resolution… CONTINUE READING