Poly-epsilon-caprolactone intravitreous devices: an in vivo study.


PURPOSE The objective of this study was to evaluate the long-term safety and pharmacokinetic profile of a dexamethasone-loaded poly-epsilon-caprolactone (PCL) intravitreous implant. METHODS The PCL devices were prepared by compression and were inserted into the vitreous of pigmented rabbits. At different time points, vitreous samples were retrieved, and… (More)
DOI: 10.1167/iovs.08-2969


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