Poly-L-ornithine promotes preferred differentiation of neural stem/progenitor cells via ERK signalling pathway

Abstract

Neural stem/progenitor cells (NSPCs) replacement therapies are the most attractive strategies to restore an injured brain. Key challenges of such therapies are enriching NSPCs and directing them differentiation into specific neural cell types. Here, three biomaterial substrates Poly-L-ornithine (PO), Poly-L-lysine (PLL) and fibronectin (FN) were… (More)
DOI: 10.1038/srep15535

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