Poly I:C-induced fever elevates threshold for shivering but reduces thermosensitivity in rabbits.

@article{Tien1995PolyIF,
  title={Poly I:C-induced fever elevates threshold for shivering but reduces thermosensitivity in rabbits.},
  author={\Oivind T\oien and James B. Mercer},
  journal={The American journal of physiology},
  year={1995},
  volume={268 5 Pt 2},
  pages={R1266-72}
}
Shivering threshold and thermosensitivity were determined in six conscious rabbits at ambient temperature (Ta) 20 and 10 degrees C before and at six different times after saline injection (0.15 ml iv) and polyriboinosinic-polyribocytidylic acid (poly I:C)-induced fever (5 micrograms/kg iv). Thermosensitivity was calculated by regression of metabolic heat production (M) and hypothalamic temperature (Thypo) during short periods (5-10 min) of square-wave cooling. Heat was extracted with a… CONTINUE READING