Poly(malic acid) nanoconjugates containing various antibodies and oligonucleotides for multitargeting drug delivery.

@article{Ljubimova2008PolymalicAN,
  title={Poly(malic acid) nanoconjugates containing various antibodies and oligonucleotides for multitargeting drug delivery.},
  author={J. Ljubimova and M. Fujita and A. Ljubimov and V. Torchilin and K. Black and E. Holler},
  journal={Nanomedicine},
  year={2008},
  volume={3 2},
  pages={
          247-65
        }
}
Nanoconjugates are emerging as promising drug-delivery vehicles because of their multimodular structure enabling them to actively target discrete cells, pass through biological barriers and simultaneously carry multiple drugs of various chemical nature. Nanoconjugates have matured from simple devices to multifunctional, biodegradable, nontoxic and nonimmunogenic constructs, capable of delivering synergistically functioning drugs in vivo. This review mainly concerns the Polycefin family of… Expand
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