Poly(dimethylsiloxane)-based microchip for two-dimensional solid-phase extraction-capillary electrophoresis with an integrated electrospray emitter tip.

@article{Dahlin2005PolydimethylsiloxanebasedMF,
  title={Poly(dimethylsiloxane)-based microchip for two-dimensional solid-phase extraction-capillary electrophoresis with an integrated electrospray emitter tip.},
  author={Andreas Pettersson Dahlin and Sara K. Bergstr{\"o}m and Per E. Andr{\'e}n and Karin E. Markides and Jonas Bergquist},
  journal={Analytical chemistry},
  year={2005},
  volume={77 16},
  pages={
          5356-63
        }
}
A microchip in poly(dimethylsiloxane) (PDMS) for in-line solid-phase extraction-capillary electrophoresis-electrospray ionization-time-of-flight mass spectrometry (SPE-CE-ESI-TOF-MS) has been developed and evaluated. The chip was fabricated in a novel one-step procedure where mixed PDMS was cast over steel wires in a mold. The removed wires defined 50-microm cylindrical channels. Fused-silica capillaries were inserted into the structure in a tight fit connection. The inner walls of the inserted… CONTINUE READING
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