Poly(acrylic acid)-cysteine for oral vitamin B12 delivery.


The aim of this study was to investigate the potential of poly(acrylic acid)-cysteine (PAA-cys) solution and microparticles to enhance the transport of vitamin B12 (VB 12) across Caco-2 cell monolayer and rat intestinal mucosa. Thiolated PAA was synthesized by covalent attachment of L-cysteine. Microparticles were prepared by spray-drying and characterized… (More)
DOI: 10.1016/j.ab.2011.08.039


Cite this paper

@article{Sarti2012PolyacrylicAF, title={Poly(acrylic acid)-cysteine for oral vitamin B12 delivery.}, author={F. Sarti and Javed Iqbal and C. R. M{\"u}ller and Gul Shahnaz and Deni Rahmat and Andreas Bernkop-Schnuerch}, journal={Analytical biochemistry}, year={2012}, volume={420 1}, pages={13-9} }