Poly(lactic acid) scaffold fabricated by gelatin particle leaching has good biocompatibility for chondrogenesis

  title={Poly(lactic acid) scaffold fabricated by gelatin particle leaching has good biocompatibility for chondrogenesis},
  author={Yihong Gong and Zu-wei Ma and Qin-Li Zhou and Jun Li and Changyou Gao and Jia-cong Shen},
  journal={Journal of Biomaterials Science, Polymer Edition},
  pages={207 - 221}
Three-dimensional poly(L-lactic acid) (PLLA) scaffolds with high porosity and an average pore size of 280–450 μm were fabricated using gelatin particles as porogen. The particles were bonded together by incubation in saturated water vapor at 70°C for 3.5 h. After casting the PLLA/1,4-dioxane solution, freeze-drying and porogen leaching with 70°C water, a porous scaffold with well-interconnected pores and some nano-fibers was obtained. The biological performance of the scaffold was evaluated by… 


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