Poly(amidoamine) (PAMAM) dendritic nanostructures for controlled sitespecific delivery of acidic anti-inflammatory active ingredient

@article{Asthana2005PolyamidoamineD,
  title={Poly(amidoamine) (PAMAM) dendritic nanostructures for controlled sitespecific delivery of acidic anti-inflammatory active ingredient},
  author={Abhay Asthana and Abhay Singh Chauhan and Prakash Vamanrao Diwan and Narendra Kumar Jain},
  journal={AAPS PharmSciTech},
  year={2005},
  volume={6},
  pages={E536-E542}
}
The purpose of the investigation was to evaluate the potential of polyamidoamine (PAMAM) dendrimer as nanoscale drug delivery units for controlled release of water insoluble and acidic anti-inflammatory drug. Flurbiprofen (FB) was selected as a model acidic anti-inflammatory drug. The aqueous solutions of 4.0 generation (G) PAMAM dendrimer in different concentrations were prepared and used further for solubilizing FB. Formation of dendrimer complex was characterized by Fourier transform… CONTINUE READING
BETA

Citations

Publications citing this paper.
SHOWING 1-10 OF 55 CITATIONS, ESTIMATED 44% COVERAGE

Non-covalent formulation of active principles with dendrimers: Current state-of-the-art and prospects for further development.

  • Journal of controlled release : official journal of the Controlled Release Society
  • 2017
VIEW 4 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

FILTER CITATIONS BY YEAR

2006
2019

CITATION STATISTICS

  • 3 Highly Influenced Citations

References

Publications referenced by this paper.
SHOWING 1-10 OF 16 REFERENCES

Preparation and evaluation of flurbiprofenloaded microemulsion for parenteral delivery

KM Park, CK Kim
  • Int J Pharm
  • 1999
VIEW 4 EXCERPTS
HIGHLY INFLUENTIAL

Dendrimer-mediated transdermal delivery: enhanced bioavailability of indomethacin.

  • Journal of controlled release : official journal of the Controlled Release Society
  • 2003
VIEW 1 EXCERPT

Similar Papers

Loading similar papers…