Poly(L-lactide): a long-term degradation study in vivo. Part III. Analytical characterization.

@article{Pistner1993PolyLlactideAL,
  title={Poly(L-lactide): a long-term degradation study in vivo. Part III. Analytical characterization.},
  author={Hans Pistner and D R Bendix and Joachim M{\"u}hling and J{\"u}rgen F. Reuther},
  journal={Biomaterials},
  year={1993},
  volume={14 4},
  pages={291-8}
}
Three poly(L-lactides) with different molecular weights were synthesized as solid blocks from the melt. Two batches were ground and small specimens were produced by injection moulding. The third block was processed by machining, yielding crystalline parts. All were implanted as small rods into the dorsal muscle of rats. The implants were recovered, weight loss was determined, and the samples analysed. The samples degraded very fast, reaching the same molecular weight level after 20 wk, then… CONTINUE READING

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