Poly(ADP-ribose) and differentiation of Friend Erythroleukemia cells. Restriction of the chain lenght.


1. Poly(ADP-ribose) synthesized in nuclei isolated from Friend erythroleukemic cells was characterized. Although the activity of poly(ADP-ribose) synthesis of cells induced to differentiate was suppressed to about one-third of that of uninduced cells, the chain length were identical, and were clearly restricted within a narrow band in polyacrylamide gels… (More)


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