Poly(ε-caprolactone)-carbon nanotube composite scaffolds for enhanced cardiac differentiation of human mesenchymal stem cells.

@article{Crowder2013PolycaprolactonecarbonNC,
  title={Poly(ε-caprolactone)-carbon nanotube composite scaffolds for enhanced cardiac differentiation of human mesenchymal stem cells.},
  author={Spencer W. Crowder and Yi Liang and Rutwik Rath and Andrew M. Park and Simon Maltais and Peter N Pintauro and William H. Hofmeister and Chee Chew Lim and Xintong Wang and Hak-Joon Sung},
  journal={Nanomedicine},
  year={2013},
  volume={8 11},
  pages={1763-76}
}
AIM To evaluate the efficacy of electrically conductive, biocompatible composite scaffolds in modulating the cardiomyogenic differentiation of human mesenchymal stem cells (hMSCs). MATERIALS & METHODS Electrospun scaffolds of poly(ε-caprolactone) with or without carbon nanotubes were developed to promote the in vitro cardiac differentiation of hMSCs. RESULTS Results indicate that hMSC differentiation can be enhanced by either culturing in electrically conductive, carbon nanotube-containing… CONTINUE READING