Poliovirus‐encoded proteinase 3C: a possible evolutionary link between cellular serine and cysteine proteinase families

@article{Gorbalenya1986PoliovirusencodedP3,
  title={Poliovirus‐encoded proteinase 3C: a possible evolutionary link between cellular serine and cysteine proteinase families},
  author={Alexander E. Gorbalenya and Vladimir M. Blinov and Alexei P. Donchenko},
  journal={FEBS Letters},
  year={1986},
  volume={194}
}
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Cross-species proteolytic processing was demonstrated by the 3C proteinases of human rhinovirus 14 and coxsackievirus B3 on poliovirus-specific polypeptide precursors, providing evidence for the existence of common conformational determinants necessary for 3C-mediated processing.
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