Pole region-dependent repression of the Drosophila gap gene Krüppel by maternal gene products.

@article{Gaul1987PoleRR,
  title={Pole region-dependent repression of the Drosophila gap gene Kr{\"u}ppel by maternal gene products.},
  author={Ulrike Gaul and Herbert Jaeckle},
  journal={Cell},
  year={1987},
  volume={51 4},
  pages={549-55}
}
We examined the protein domain of the gap gene Krüppel (Kr) in mutants that affect the establishment of different regions of the segment pattern along the longitudinal axis of the Drosophila embryo. Our data suggest that Kr provides cues for establishing the "central" pattern elements at the blastoderm stage, and that Kr activity is controlled by maternal effect genes acting at the poles. The formation of the Kr protein domain may involve ubiquitous activation of Kr gene expression which… CONTINUE READING

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