Polarized exocytosis and transcytosis of Notch during its apical localization in Drosophila epithelial cells.

@article{Sasaki2007PolarizedEA,
  title={Polarized exocytosis and transcytosis of Notch during its apical localization in Drosophila epithelial cells.},
  author={Nobuo Sasaki and Takeshi Sasamura and Hiroyuki Ishikawa and Maiko Kanai and Ryu Ueda and Kaoru Saigo and Kenji Matsuno},
  journal={Genes to cells : devoted to molecular & cellular mechanisms},
  year={2007},
  volume={12 1},
  pages={89-103}
}
Notch (N) and its ligands, Delta (Dl) and Serrate (Ser), are transmembrane proteins that mediate the cell-cell interactions necessary for many cell-fate decisions. In Drosophila, N is predominantly localized to the apical portion of epithelial cells, but the mechanisms and functions of this localization are unknown. Here, we found N, Dl, and Ser were mostly located in the region from the subapical complex (SAC) to the apical portion of the adherens junctions (AJs) in wing disc epithelium. N was… CONTINUE READING

From This Paper

Topics from this paper.
23 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 23 extracted citations

Similar Papers

Loading similar papers…