Polarized calcium and calmodulin signaling in secretory epithelia.

@article{Ashby2002PolarizedCA,
  title={Polarized calcium and calmodulin signaling in secretory epithelia.},
  author={Michael C. Ashby and Alexei V Tepikin},
  journal={Physiological reviews},
  year={2002},
  volume={82 3},
  pages={701-34}
}
This review examines polarized calcium and calmodulin signaling in exocrine epithelial cells. The calcium ion is a simple, evolutionarily ancient, and universal second messenger. In exocrine epithelial cells, it regulates essential functions such as exocytosis, fluid secretion, and gene expression. Exocrine cells are structurally polarized, with the apical… CONTINUE READING