Polarization of Chemokine Receptors to the Leading Edge during Lymphocyte Chemotaxis

Abstract

Leukocyte migration in response to cell attractant gradients or chemotaxis is a key phenomenon both in cell movement and in the inflammatory response. Chemokines are quite likely to be the key molecules directing migration of leukocytes that involve cell polarization with generation of specialized cell compartments. The precise mechanism of leukocyte… (More)

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