Polarity index of pharmacological agents used for maintenance treatment of bipolar disorder

@article{Popovic2012PolarityIO,
  title={Polarity index of pharmacological agents used for maintenance treatment of bipolar disorder},
  author={D. Popovic and M. Reinares and J. Goikolea and C. Bonn{\'i}n and A. Gonz{\'a}lez-Pinto and E. Vieta},
  journal={European Neuropsychopharmacology},
  year={2012},
  volume={22},
  pages={339-346}
}
Over one half of bipolar patients have been reported to be more prone to either depressive or manic relapses. This study aimed to define profiles of drugs used for maintenance treatment of bipolar disorder (BD) by the means of Polarity Index. Polarity Index is a new metric indicating the relative antimanic versus antidepressive preventive efficacy of drugs. Polarity Index was retrieved by calculating Number Needed to Treat (NNT) for prevention of depression and NNT for prevention of mania ratio… Expand
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