Polarity-dependent effects of transcranial direct current stimulation in obsessive-compulsive disorder.

@article{DUrso2016PolaritydependentEO,
  title={Polarity-dependent effects of transcranial direct current stimulation in obsessive-compulsive disorder.},
  author={Giordano D'Urso and Andr{\'e} Russowsky Brunoni and Annalisa Anastasia and Marco Micillo and Andrea de Bartolomeis and Antonio Mantovani},
  journal={Neurocase},
  year={2016},
  volume={22 1},
  pages={60-4}
}
About one third of patients with obsessive-compulsive disorder (OCD) fail to experience significant clinical benefit from currently available treatments. Hyperactivity of the presupplementary motor area (pre-SMA) has been detected in OCD patients, but it is not clear whether it is the primary cause or a secondary compensatory mechanism in OCD pathophysiology. Transcranial direct current stimulation (tDCS) is a noninvasive brain stimulation technique with polarity-dependent effects on motor… CONTINUE READING

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