Polar assembly of the type IV pilus secretin in Myxococcus xanthus.

@article{Nudleman2006PolarAO,
  title={Polar assembly of the type IV pilus secretin in Myxococcus xanthus.},
  author={Eric N Nudleman and Daniel Wall and Dale Kaiser},
  journal={Molecular microbiology},
  year={2006},
  volume={60 1},
  pages={16-29}
}
The type IV pilus filament of Myxococcus xanthus penetrates the outer membrane through a gated channel--the PilQ secretin. Assembly of the channel and formation of PilQ multimeric complexes that resist disassembly in heated detergent is correlated with the release of a 50 kDa fragment of PilQ. Tgl lipoprotein is required for PilQ assembly in M. xanthus, because PilQ monomers but no heat and detergent-resistant complexes are present in a strain from which tgl has been deleted. PilQ protein is… CONTINUE READING

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