Polaprezinc protects human colon cells from oxidative injury induced by hydrogen peroxide: relevant to cytoprotective heat shock proteins.

@article{Ohkawara2006PolaprezincPH,
  title={Polaprezinc protects human colon cells from oxidative injury induced by hydrogen peroxide: relevant to cytoprotective heat shock proteins.},
  author={Tatsuya Ohkawara and Jun Nishihira and Rikako Nagashima and Hiroshi Takeda and Masahiro Asaka},
  journal={World journal of gastroenterology},
  year={2006},
  volume={12 38},
  pages={
          6178-81
        }
}
AIM To investigate the effect of polaprezinc on cellular damage induced by hydrogen peroxide (H(2)O(2)) in human colon CaCo2 cells. METHODS CaCo2 cells were treated with polaprezinc (10-100 micromol/L) for 6 h. After polaprezinc treatment, the cells were incubated with H(2)O(2) (20 micromol/L) for 1 h. Cell viability was measured by MTT assay. Western blot analysis for heat shock protein (HSP) 27 and HSP72 in the cells was performed. Moreover, cells were pretreated with quercetin (200… Expand
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