PolY, a transcriptional regulator with ATPase activity, directly activates transcription of polR in polyoxin biosynthesis in Streptomyces cacaoi.

@article{Li2010PolYAT,
  title={PolY, a transcriptional regulator with ATPase activity, directly activates transcription of polR in polyoxin biosynthesis in Streptomyces cacaoi.},
  author={Rui Li and Guo Zhao and Zhoujie Xie and Xihong He and Wenqing Chen and Zixin Deng and Huarong Tan},
  journal={Molecular microbiology},
  year={2010},
  volume={75 2},
  pages={349-64}
}
polY, a transcriptional regulatory gene in the polyoxin biosynthetic cluster of Streptomyces cacaoi, was analysed, and its deduced product (PolY) showed amino acid sequence homology to AfsR from Streptomyces coelicolor A3(2). PolY contains an OmpR-like DNA binding domain at its N-terminal and an ATPase domain in the middle of the protein. Disruption of polY… CONTINUE READING