Pol II and its associated epigenetic marks are present at pol III-transcribed non-coding RNA genes

@inproceedings{Barski2010PolIA,
  title={Pol II and its associated epigenetic marks are present at pol III-transcribed non-coding RNA genes},
  author={Artem Barski and Iouri Chepelev and Dritan Liko and Suresh Cuddapah and Alastair B Fleming and Joanna L Birch and Kairong Cui and Robert J. White and Keji Zhao},
  booktitle={Nature Structural &Molecular Biology},
  year={2010}
}
Epigenetic control is an important aspect of gene regulation. Despite detailed understanding of protein-coding gene expression, the transcription of noncoding RNA genes by RNA polymerase III (Pol III) is less well characterized. Here we profile the epigenetic features of Pol III target genes throughout the human genome. This reveals that the chromatin landscape of Pol III–transcribed genes resembles that of Pol II templates in many ways, although there are also clear differences. Our analysis… CONTINUE READING
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