Poisoning with 1-propanol and 2-propanol

@article{Vujasinovic2007PoisoningW1,
  title={Poisoning with 1-propanol and 2-propanol},
  author={Miroslav Vujasinovic and Mustafa Koçar and K Kramer and Matja{\vz} Bunc and Miran Brvar},
  journal={Human and Experimental Toxicology},
  year={2007},
  volume={26},
  pages={975 - 978}
}
1-Propanol and 2-propanol are isomers of an alcohol with three carbons. They are colorless liquids with a sweet odor. 1-Propanol is metabolized by alcohol dehydrogenase to propionic acid and presents with metabolic acidosis and elevated anion gap, whereas 2-propanol is metabolized by alcohol dehydrogenase to acetone and presents with rapidly developing (within 3–4 h after exposure) ketosis and ketonuria but without metabolic acidosis. We report a patient who simultaneously ingested a lethal… Expand
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  • 2010
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The reactions and pathways that account for the metabolism of acetone in humans are described and it is shown that acetone derived from the non-enzymatic breakdown of acetoacetate in ketotic individuals or from the oxidation of ingested isopropanol can be metabolized to D-lactate and pyruvate, and ultimately glucose. Expand
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