Points of Action of Estrogen Antagonists and a Calmodulin Antagonist within the MCF-7 Human Breast Cancer Cell Cycle1

Abstract

Tamoxifen and other structurally related nonsteroidal antiestrogens possess properties in addition to their estrogen antagonist activity includ ing inhibition of both calmodulin and protein kinase C. The present studies were designed to test whether the estrogen-reversible (estrogen receptor mediated) and estrogen-irreversible effects of nonsteroidal… (More)

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Cite this paper

@inproceedings{Musgrove2006PointsOA, title={Points of Action of Estrogen Antagonists and a Calmodulin Antagonist within the MCF-7 Human Breast Cancer Cell Cycle1}, author={Elizabeth A. Musgrove and Alan E. Wakeling and Robert Lyndsay Sutherland}, year={2006} }