Point-of-care breath test for biomarkers of active pulmonary tuberculosis.

@article{Phillips2012PointofcareBT,
  title={Point-of-care breath test for biomarkers of active pulmonary tuberculosis.},
  author={Michael Phillips and Victoria Basa-Dalay and Jaime D. Blais and Graham Henry Bothamley and Anirudh Chaturvedi and Kinjal D Modi and Mauli S Pandya and Maria Piedad R Natividad and Urvish Patel and Nagsen Nirgun Ramraje and Peter Schmitt and Zarir Farokh Udwadia},
  journal={Tuberculosis},
  year={2012},
  volume={92 4},
  pages={314-20}
}
RATIONALE Volatile organic compounds (VOCs) in breath provide biomarkers of tuberculosis (TB) because Mycobacterium tuberculosis manufactures VOC metabolites that are detectable in the breath of infected patients. OBJECTIVES We evaluated breath VOC biomarkers in subjects with active pulmonary TB, using an internet-linked rapid point-of-care breath test. METHODS 279 subjects were studied at four centers in three countries, Philippines, UK, and India, and data was analyzed from 251 (130… CONTINUE READING

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