Point mutations of the N‐ras gene in the blood plasma DNA of patients with myelodysplastic syndrome or acute myelogenous leukaemia

@article{Vasioukhin1994PointMO,
  title={Point mutations of the N‐ras gene in the blood plasma DNA of patients with myelodysplastic syndrome or acute myelogenous leukaemia},
  author={Valeri Vasioukhin and Philippe Anker and Pierre Maurice and Jacqueline Lyautey and Christine Lederrey and Maurice Stroun},
  journal={British Journal of Haematology},
  year={1994},
  volume={86}
}
Summary. Oncogene mutations are frequently found in several tumour types and, among these, point mutations of the ras gene are particularly significant. A predominance of N‐ras mutations has been found in the bone marrow DNA of patients with myelodysplatic syndrome (MDS) or acute myelogenous leukaemia (AML). On the other hand, increased levels of plasma DNA have previously been observed in patients suffering from various malignant diseases. In the present work we have investigated, by… 
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