Point‐of‐care testing in haemostasis

@article{Perry2010PointofcareTI,
  title={Point‐of‐care testing in haemostasis},
  author={David J. Perry and David A Fitzmaurice and Steve Kitchen and Ian J. Mackie and Susan Mallett},
  journal={British Journal of Haematology},
  year={2010},
  volume={150}
}
Point‐of‐care testing (POCT) in haematology has seen a significant increase in both the spectrum of tests available and the number of tests performed annually. POCT is frequently undertaken with the belief that this will reduce the turnaround time for results and so improve patient care. The most obvious example of POCT in haemostasis is the out‐of‐hospital monitoring of the International Normalized Ratio in patients receiving a vitamin K antagonist, such as warfarin. Other areas include the… 
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118 Citations
Highly Influential Citations
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Background Citations
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Methods Citations
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118 Citations

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Citation Type

Where are we at with point‐ of‐ care testing in haematology?
TLDR
Clinical studies that validate the use of POCT devices and a lack of training, poor standardization in obtaining blood samples and insufficient internal/external quality assessment are discussed.
Point-of-Care Testing in Hemostasis
Point-of-care testing (POCT) provides a rapid service that may be useful in life-threatening situations, to inform urgent therapeutic decisions, and manage long term conditions. The main haemostasis…
Benefits and Pitfalls of Point-of-Care Coagulation Testing for Anticoagulation Management: An ACLPS Critical Review
  • G. Wool
  • Medicine
    American journal of clinical pathology
  • 2019
TLDR
Point-of-care coagulation testing for anticoagulation monitoring can offer significant advantages in particular situations: patient-managed warfarin therapy as well as rapid turnaround time heparin management for intraoperative patients.
Point-of-care test (POCT) INR: hope or illusion?
TLDR
The international normalized ratio, INR point-of-care test (POCT INR), is the main test of this new proposal, which has great potential benefit in situations where the quick INR results influences clinical decision making, as in acute ischemic stroke, before surgical procedures and during cardiac surgery.
The Use of Point of Care Testing for Monitoring of APTT in Patients Receiving Heparin Infusion
TLDR
Whether APTT Point of Care Testing (POCT) in post-operative cardiac surgery patients on heparin infusion is accurate when compared to centralized laboratory tests is determined.
Point of Care Assessment of Coagulation.
TLDR
It is unlikely that a single test would be ideal for assessing the complete coagulation status of all patients; therefore, the ideal combination of tests for a specific patient needs to be determined based on an understanding of the underlying disease, and protocols must be standardized to minimize interoperator and interinstitutional variability.
Heparin monitoring: From blood tube to microfluidic device
TLDR
The future of coagulation testing could see a move away from the more traditional clot-based tests towards more modern analytical technologies, with a knock-on effect of improved assay variability, precision, and reliability.
Analytical performance of a point-of-care device in monitoring patients on oral anticoagulation with vitamin K antagonists
TLDR
The accuracy and precision of this point-of-care device is moderate and may have potential utility only where access to a reference lab is difficult.
Correlation of activated clotting times and standard laboratory coagulation tests in paediatric non-cardiac surgery
TLDR
Intraoperative measurement of ACT did not provide comparable thresholds of normal haemostasis as compared to standard coagulation testing, and the median ACT values remained within the normal range throughout the entire surgical phase, while standardCoagulation tests were mostly abnormal during surgery.
Point-of-care derived INR does not reliably detect significant coagulopathy following Australian snakebite.
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References

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TLDR
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TLDR
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TLDR
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TLDR
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