Point: Flow-mediated dilation does reflect nitric oxide-mediated endothelial function.

@article{Green2005PointFD,
  title={Point: Flow-mediated dilation does reflect nitric oxide-mediated endothelial function.},
  author={Daniel J. Green},
  journal={Journal of applied physiology},
  year={2005},
  volume={99 3},
  pages={
          1233-4; discussion 1237-8
        }
}
  • D. Green
  • Published 1 September 2005
  • Medicine
  • Journal of applied physiology
Before you embark on this debate with my redoubtable Canadian friends, you may find it advisable to take something to minimize your cardiovascular risk. I recommend the sensible precaution of a bottle of excellent Australian Shiraz. Pour yourself a generous measure and take a few sips. Now, if your 
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126 Citations
Highly Influential Citations
3
Background Citations
40
Methods Citations
11
Results Citations
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126 Citations

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Citation Type

Flow-mediated vasodilation is mediated by endothelium-derived nitric oxide.
  • M. Creager
  • Medicine
    Journal of applied physiology
  • 2005
This letter is in response to the Point:Counterpoint series “Flow-mediated dilation does/does not reflect nitric oxide-mediated endothelial function” that appeared in the September issue (vol. 99: ...
Flow-mediated vasodilation partially reflects nitric oxide-mediated endothelial function.
This letter is in response to the Point:Counterpoint series “Flow-mediated dilation does/does not reflect nitric oxide-mediated endothelial function” that appeared in the September issue (vol. 99:…
Flow-mediated dilation does/does not reflect nitric oxide-mediated endothelial function.
  • C. Austin
  • Biology
    Journal of applied physiology
  • 2005
This letter is in response to the Point:Counterpoint series “Flow-mediated dilation does/does not reflect nitric oxide-mediated endothelial function” that appeared in the September issue (vol. 99:…
FMD vs. pharmacological approaches for endothelial function.
This letter is in response to the Point:Counterpoint series “Flow-mediated dilation does/does not reflect nitric oxide-mediated endothelial function” that appeared in the September issue (vol. 99: ...
Comment on Point:Counterpoint "Flow-mediated dilation does/does not reflect nitric oxide-mediated endothelial function".
  • M. Joyner
  • Biology
    Journal of applied physiology
  • 2005
This letter is in response to the Point-Counterpoint series “Flow-mediated dilation does/does not reflect nitric oxide-mediated endothelial function.” that appeared in the September issue (vol. 99:…
Brachial artery FMD with 5-minute distal cuff occlusion--a useful pathophysiological test after all!
This letter is in response to the Point:Counterpoint series “Flow-mediated dilation does/does not reflect nitric oxide-mediated endothelial function” that appeared in the September issue (vol. 99: ...
Flow-mediated dilation.
This letter is in response to the Point:Counterpoint series “Flow-mediated dilation does/does not reflect nitric oxide-mediated endothelial function” that appeared in the September issue (vol. 99: ...
Flow-mediated dilation and biological variability.
This letter is in response to the Point:Counterpoint series “Flow-mediated dilation does/does not reflect nitric oxide-mediated endothelial function” that appeared in the September issue (vol. 99:…
In FMD, NO is actually "the middle man".
This letter is in response to the Point:Counterpoint series “Flow-mediated dilation does/does not reflect nitric oxide-mediated endothelial function” that appeared in the September issue (vol. 99:…
Reliability of low‐flow vasoreactivity in the brachial artery of adolescents
TLDR
The day‐to‐day reliability of low‐flow‐mediated constriction (L‐FMC) and composite vessel reactivity (CVR) and the relationship between FMD and FMD is investigated in adolescents.
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References

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Endothelial dysfunction: does it matter? Is it reversible?
  • D. Celermajer
  • Medicine, Biology
    Journal of the American College of Cardiology
  • 1997
Guidelines for the ultrasound assessment of endothelial-dependent flow-mediated vasodilation of the brachial artery: a report of the International Brachial Artery Reactivity Task Force.
EFFECTS OF ENDOTHELIUM-DERIVED NITRIC OXIDE ON PERIPHERAL ARTERIOLAR TONE IN MAN
Sympathetic activation markedly reduces endothelium-dependent, flow-mediated vasodilation.
Contribution of vasodilator prostanoids and nitric oxide to resting flow, metabolic vasodilation, and flow-mediated dilation in human coronary circulation.
TLDR
Tonic release of vasodilator prostanoids and NO contributes to resting conduit and resistance vessel tone and to peak functional hyperemia and flow-mediated dilation after metabolic stimulation, and suggests that it may be a key mechanism for preventing myocardial ischemia in coronary artery disease.
Endothelial Dysfunction and Cardiovascular Risk Prediction in Peripheral Arterial Disease: Additive Value of Flow-Mediated Dilation to Ankle-Brachial Pressure Index
TLDR
A low brachial artery FMD is an independent predictor of cardiovascular risk in patients with PAD and adds to the prognostic value of ABPI, which is currently the most powerful prognostic indicator in PAD.
The clinical implications of endothelial dysfunction.
Flow-mediated vasodilation of the femoral and brachial artery induced by exercise in healthy nonsmoking and smoking men.
Endothelium-dependent dilation in the systemic arteries of asymptomatic subjects relates to coronary risk factors and their interaction.
Nitric oxide is responsible for flow-dependent dilatation of human peripheral conduit arteries in vivo.
TLDR
No, but not prostacyclin, is essential for flow-mediated dilatation of large human arteries, and this response can be used as a test for the L-arginine/NO pathway in clinical studies.
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