• DOI:10.1152/japplphysiol.00182.2010
Corpus ID: 7685157

Point: Chronic activation of the sympathetic nervous system is the dominant contributor to systemic hypertension.

@article{Esler2010PointCA,
  title={Point: Chronic activation of the sympathetic nervous system is the dominant contributor to systemic hypertension.},
  author={M. Esler and E. Lambert and M. Schlaich},
  journal={Journal of applied physiology},
  year={2010},
  volume={109 6},
  pages={
          1996-8; discussion 2016
        }
}

• M. Esler, E. Lambert, M. Schlaich
• Published 2010
• Medicine
• Journal of applied physiology

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For the past three decades, the renin-angiotensin system has been the major focus in high blood pressure research. The proven value of antihypertensive drugs that block this system has deflected research from other blood pressure-raising systems, including the sympathetic nervous system. Despite