Poetry in motion: Increased chromosomal mobility after DNA damage.

@article{Smith2017PoetryIM,
  title={Poetry in motion: Increased chromosomal mobility after DNA damage.},
  author={Michael A. Smith and Rodney Rothstein},
  journal={DNA repair},
  year={2017},
  volume={56},
  pages={
          102-108
        }
}
Double-strand breaks (DSBs) are among the most lethal DNA lesions, and a variety of pathways have evolved to manage their repair in a timely fashion. One such pathway is homologous recombination (HR), in which information from an undamaged donor site is used as a template for repair. Although many of the biochemical steps of HR are known, the physical movements of chromosomes that must underlie the pairing of homologous sequence during mitotic DSB repair have remained mysterious. Recently… CONTINUE READING
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