Podophyllotoxin: a novel potential natural anticancer agent

@article{Ardalani2017PodophyllotoxinAN,
  title={Podophyllotoxin: a novel potential natural anticancer agent},
  author={Hamidreza Ardalani and Amir Avan and Majid Ghayour-Mobarhan},
  journal={Avicenna Journal of Phytomedicine},
  year={2017},
  volume={7},
  pages={285 - 294}
}
Objective: The aim of the present review is to give an overview about the role, biosynthesis, and characteristics of Podophyllotoxin (PTOX) as a potential antitumor agent with particular emphasis on key biosynthesis processes, function of related enzymes and characterization of genes encoding the enzymes. Materials and Methods: Google scholar, PubMed and Scopus were searched for literatures which have studied identification, characterization, fermentation and therapeutic effects of PTOX and… 

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