Podocytes populate cellular crescents in a murine model of inflammatory glomerulonephritis.

@article{Moeller2004PodocytesPC,
  title={Podocytes populate cellular crescents in a murine model of inflammatory glomerulonephritis.},
  author={M. Moeller and Abdulsalaam Soofi and I. Hartmann and M. Le Hir and R. Wiggins and W. Kriz and L. Holzman},
  journal={Journal of the American Society of Nephrology : JASN},
  year={2004},
  volume={15 1},
  pages={
          61-7
        }
}
Cellular crescents are a defining histologic finding in many forms of inflammatory glomerulonephritis. Despite numerous studies, the origin of glomerular crescents remains unresolved. A genetic cell lineage-mapping study with a novel transgenic mouse model was performed to investigate whether visceral glomerular epithelial cells, termed podocytes, are precursors of cells that populate cellular crescents. The podocyte-specific 2.5P-Cre mouse line was crossed with the ROSA26 reporter line… Expand
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