Podocytes Express IL-6 and Lipocalin 2/ Neutrophil Gelatinase-Associated Lipocalin in Lipopolysaccharide-Induced Acute Glomerular Injury

@inproceedings{Lee2012PodocytesEI,
  title={Podocytes Express IL-6 and Lipocalin 2/ Neutrophil Gelatinase-Associated Lipocalin in Lipopolysaccharide-Induced Acute Glomerular Injury},
  author={Sarah J. Lee and Emily Borsting and Anne-{\'E}milie Decl{\`e}ves and Prabhleen Singh and Robyn Cunard},
  booktitle={Nephron. Experimental nephrology},
  year={2012}
}
BACKGROUND/AIMS Acute kidney injury (AKI) contributes to significant morbidity and mortality in the intensive care unit (ICU). Plasma levels of interleukin (IL)-6 predict the development of AKI and are associated with higher mortality in ICU patients with AKI. Most studies in AKI have focused on the tubulo-interstitium, despite evidence of glomerular involvement. In the following study, our goals were to investigate the expression of IL-6 and its downstream mediators in septic-induced AKI… CONTINUE READING

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