Podocyte Injury and Albuminuria in Experimental Hyperuricemic Model Rats

Abstract

Although hyperuricemia is shown to accelerate chronic kidney disease, the mechanisms remain unclear. Accumulating studies also indicate that uric acid has both pro- and antioxidant properties. We postulated that hyperuricemia impairs the function of glomerular podocytes, resulting in albuminuria. Hyperuricemic model was induced by oral administration of 2… (More)
DOI: 10.1155/2017/3759153

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Cite this paper

@inproceedings{Asakawa2017PodocyteIA, title={Podocyte Injury and Albuminuria in Experimental Hyperuricemic Model Rats}, author={Shinichiro Asakawa and Shigeru Shibata and Chikayuki Morimoto and Takeshi Shiraishi and Takashi Nakamura and Yoshifuru Tamura and Takanori Kumagai and Makoto Hosoyamada and Shunya Uchida}, booktitle={Oxidative medicine and cellular longevity}, year={2017} }