Pneumocystis pneumonia in an HIV-negative patient with no overt risk factors on presentation.

@article{Sandhu2010PneumocystisPI,
  title={Pneumocystis pneumonia in an HIV-negative patient with no overt risk factors on presentation.},
  author={Geeta Sandhu and Riddhi Dasgupta and Aditi Ranade and M. Baskin},
  journal={The European respiratory journal},
  year={2010},
  volume={35 4},
  pages={927-9}
}
individuals are genetically predisposed to over-express HLA-G in response to specific signals. Once secreted, HLA-G could promote a cascade of events that result in worsening inflammation. Several polymorphisms in the promoter region of HLA-G coincide with transcription factor binding sites could account for inter-individual differences in expression of HLA-G [10]. We previously identified a polymorphism in the 3’ untranslated region of HLA-G which disrupts a microRNA target site and… CONTINUE READING

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