Pneumocystis carinii contains a functional cell-division-cycle Cdc2 homologue.

  title={Pneumocystis carinii contains a functional cell-division-cycle Cdc2 homologue.},
  author={Charles Thomas and Robert Albert Anders and Michael P. Gustafson and Edward B. Leof and Andrew H. Limper},
  journal={American journal of respiratory cell and molecular biology},
  volume={18 3},
Pneumocystis carinii causes life-threatening pneumonia in immunocompromised patients. The inability to culture P. carinii has hampered basic investigations of the organism's life cycle, limiting the development of new therapies directed against it. Recent investigations indicate that P. carinii is a fungus phylogenetically related to other ascomycetes such as Schizosaccharomyces pombe. The cell cycles of S. pombe and homologous fungi are carefully regulated by cell-division-cycle molecules (cdc… CONTINUE READING