Pneumococcal seroconversion after vaccination for children with atopic dermatitis treated with tacrolimus ointment.

@article{Stiehm2005PneumococcalSA,
  title={Pneumococcal seroconversion after vaccination for children with atopic dermatitis treated with tacrolimus ointment.},
  author={E. Richard Stiehm and Robert Lloyd Roberts and Michael S Kaplan and Jonathan Corren and Eileen Jaracz and Mikaela Rico},
  journal={Journal of the American Academy of Dermatology},
  year={2005},
  volume={53 2 Suppl 2},
  pages={S206-13}
}
OBJECTIVE We sought to determine the effect of treatment with topical tacrolimus on B- and T-cell immunity including the primary antibody response to pneumococcal polysaccharide vaccine in children with atopic dermatitis. METHODS In this open-label, noncomparative study, 23 children aged 2 to 12 years with moderate to severe atopic dermatitis were treated with tacrolimus 0.03% ointment twice daily for 7 weeks, immunized with a 23-valent pneumococcal polysaccharide vaccine after 3 weeks of… CONTINUE READING
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