Pneumococcal infections after human bone-marrow transplantation.

  title={Pneumococcal infections after human bone-marrow transplantation.},
  author={Drew J. Winston and Gerald Schiffman and David C. C. Wang and Stephen A. Feig and Chih Hung Lin and E L Marso and Winston G. Ho and Lowell S. Young and Robert Peter Gale},
  journal={Annals of internal medicine},
  volume={91 6},
Seven of 26 long-term survivors (greater than 7 months post-transplant) of bone-marrow transplantation developed penicillin-sensitive pneumococcal infections more than 7 months after transplantation. One patient had two infections. Six of eight infections were associated with pneumococcal bacteremia, and Streptococcus pneumoniae type 6A was isolated in three cases. Two infections were fatal. All patients had normal nematopoietic function, and none was receiving immunosuppressive therapy. The… CONTINUE READING
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