Pneumococcal coinfection with human metapneumovirus.

  title={Pneumococcal coinfection with human metapneumovirus.},
  author={Shabir A Madhi and Herbert P. Ludewick and Locadiah Kuwanda and Nadia van Niekerk and Clare Louise Cutland and Tessa Little and Keith P. Klugman},
  journal={The Journal of infectious diseases},
  volume={193 9},
BACKGROUND Infection with the newly discovered human metapneumovirus (hMPV) may lead to hospitalization of children with lower respiratory tract infection (LRTI), although the pathogenesis thereof remains to be elucidated. METHODS This hypothesis-generating study involved a cohort of children randomized to receive 9-valent conjugate pneumococcal vaccine or placebo and who were tested for hMPV infection when hospitalized for LRTI. By use of a nested reverse-transcription polymerase chain… CONTINUE READING
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